Sunday, May 12, 2019

Cell Biology vs Systems Biology

Cell biology is the integration of molecular biology with biochemistry and physiology explaining how the living cell grows, divides and evolves.

Systems Biology is a paradigm defined in antithesis to the reductionist paradigm.

Two recurrent motifs in cell biology are highlighted :
1. The interconnectedness of physiological, organizational and regulatory processes in the cell.
2. Strategies to intervene in these complex processes to manipulate an organism for scientific, biotechnological and medical purposes

1. Description of the mechanisms describing the flow of information

1. The Central Dogma of Molecular Biology deals with the detailed residue by residue transfer of sequential information. It states that information cannot be transferred back from protein to either protein or nucleic acid.

Transmission of information is not one-way.

2. Describe key regulatory points in the transcription, post-transcriptional, translational and post-translational control

There are no programs at any (other) level.

3. Describe the mechanism behind selected bacterial networks

There is no genetic program.

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